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Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

Ubiquitin (Ub) has important roles in a wide range of intracellular signalling pathways. In the conventional view, ubiquitin alters the signalling activity of the target protein through covalent modification, but accumulating evidence points to the emerging role of non-covalent interaction between u...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Peisley, Alys, Wu, Bin, Xu, Hui, Chen, Zhijian J., Hur, Sun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136653/
https://ncbi.nlm.nih.gov/pubmed/24590070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13140
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