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Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments
The viral sensor MDA5 distinguishes between cellular and viral dsRNAs by length-dependent recognition in the range of ∼0.5–7 kb. The ability to discriminate dsRNA length at this scale sets MDA5 apart from other dsRNA receptors of the immune system. We have shown previously that MDA5 forms filaments...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523859/ https://ncbi.nlm.nih.gov/pubmed/23129641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208618109 |
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