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The multifaceted role of chromosomal instability in cancer and its microenvironment
Chromosomal instability (CIN) is a hallmark of human cancer and it is associated with poor prognosis, metastasis, and therapeutic resistance. CIN results from errors in chromosome segregation during mitosis leading to structural and numerical chromosomal abnormalities. In addition to generating geno...
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| Publicado no: | Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6136429/ https://ncbi.nlm.nih.gov/pubmed/30193109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.027 |
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