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Mechanisms of Chromosomal Instability

Most solid tumors are aneuploid, having a chromosome number that is not a multiple of the haploid number, and many frequently mis-segregate whole chromosomes in a phenomenon called chromosomal instability (CIN). CIN positively correlates with poor patient prognosis, indicating that reduced mitotic f...

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Bibliografski detalji
Glavni autori: Thompson, Sarah L., Bakhoum, Samuel F., Compton, Duane A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781365/
https://ncbi.nlm.nih.gov/pubmed/20334839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.034
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