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Mechanisms of Chromosomal Instability
Most solid tumors are aneuploid, having a chromosome number that is not a multiple of the haploid number, and many frequently mis-segregate whole chromosomes in a phenomenon called chromosomal instability (CIN). CIN positively correlates with poor patient prognosis, indicating that reduced mitotic f...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781365/ https://ncbi.nlm.nih.gov/pubmed/20334839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.034 |
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