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Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities

DNA double-strand breaks (DSBs) prevents cells from entering mitosis in the presence of genomic damage. Little is known about the response to DSBs once cells have already committed to mitosis. Here we review the genome-protective role of mitotic DNA damage response and evidence suggesting that its u...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Trends Cancer
Main Authors: Bakhoum, Samuel F., Kabeche, Lilian, Compton, Duane A., Powell, Simon N., Bastians, Holger
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518619/
https://ncbi.nlm.nih.gov/pubmed/28718433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.02.001
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