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Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities
DNA double-strand breaks (DSBs) prevents cells from entering mitosis in the presence of genomic damage. Little is known about the response to DSBs once cells have already committed to mitosis. Here we review the genome-protective role of mitotic DNA damage response and evidence suggesting that its u...
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| Pubblicato in: | Trends Cancer |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518619/ https://ncbi.nlm.nih.gov/pubmed/28718433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.02.001 |
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