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Chromosomal instability and cancer: a complex relationship with therapeutic potential
Chromosomal instability (CIN) is a hallmark of human neoplasms. Despite its widespread prevalence, knowledge of the mechanisms and contributions of CIN in cancer has been elusive. It is now evident that the role of CIN in tumor initiation and growth is more complex than previously thought. Furthermo...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314464/ https://ncbi.nlm.nih.gov/pubmed/22466654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59954 |
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