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A CINful way to overcome addiction: how chromosomal instability enables cancer to overcome its oncogene addiction
Oncogene‐addicted tumors present a valuable target for therapeutic intervention and an opportunity to achieve a wide therapeutic window. Nonetheless, resistance to targeted therapies is frequently observed and it arises through multiple mechanisms, including mutations in the target gene. Chromosomal...
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| 發表在: | EMBO Mol Med |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059011/ https://ncbi.nlm.nih.gov/pubmed/32072755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012017 |
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