The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation

The development of midbrain dopaminergic (mDA) neurons is controlled by multiple morphogens and transcription factors. However, little is known about the role of extracellular matrix proteins in this process. Here we examined the function of roof plate-specific spondins (RSPO1-4) and the floor plate...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Gyllborg, Daniel, Ahmed, Maqsood, Toledo, Enrique M., Theofilopoulos, Spyridon, Yang, Shanzheng, ffrench-Constant, Charles, Arenas, Ernest
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135723/
https://ncbi.nlm.nih.gov/pubmed/30146491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.07.014
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