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The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation

The development of midbrain dopaminergic (mDA) neurons is controlled by multiple morphogens and transcription factors. However, little is known about the role of extracellular matrix proteins in this process. Here we examined the function of roof plate-specific spondins (RSPO1-4) and the floor plate...

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Pubblicato in:Stem Cell Reports
Autori principali: Gyllborg, Daniel, Ahmed, Maqsood, Toledo, Enrique M., Theofilopoulos, Spyridon, Yang, Shanzheng, ffrench-Constant, Charles, Arenas, Ernest
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135723/
https://ncbi.nlm.nih.gov/pubmed/30146491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.07.014
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