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The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation

The development of midbrain dopaminergic (mDA) neurons is controlled by multiple morphogens and transcription factors. However, little is known about the role of extracellular matrix proteins in this process. Here we examined the function of roof plate-specific spondins (RSPO1-4) and the floor plate...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Gyllborg, Daniel, Ahmed, Maqsood, Toledo, Enrique M., Theofilopoulos, Spyridon, Yang, Shanzheng, ffrench-Constant, Charles, Arenas, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135723/
https://ncbi.nlm.nih.gov/pubmed/30146491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.07.014
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