PTENα regulates mitophagy and maintains mitochondrial quality control

PTEN plays an important role in tumor suppression, and PTEN family members are involved in multiple biological processes in various subcellular locations. Here we report that PTENα, the first identified PTEN isoform, regulates mitophagy through promotion of PARK2 recruitment to damaged mitochondria....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Li, Guoliang, Yang, Jingyi, Yang, Chunyuan, Zhu, Minglu, Jin, Yan, McNutt, Michael A., Yin, Yuxin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper - Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135630/
https://ncbi.nlm.nih.gov/pubmed/29969932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489477
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker