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PTENα regulates mitophagy and maintains mitochondrial quality control
PTEN plays an important role in tumor suppression, and PTEN family members are involved in multiple biological processes in various subcellular locations. Here we report that PTENα, the first identified PTEN isoform, regulates mitophagy through promotion of PARK2 recruitment to damaged mitochondria....
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| Publicado en: | Autophagy |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135630/ https://ncbi.nlm.nih.gov/pubmed/29969932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489477 |
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