Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply

Normal metabolism requires a controlled balance between anabolism and catabolism. It is not completely known how this balance can be retained when the level of nutrient supply changes in the long term. We found that in murine liver anabolism, as represented by the phosphorylation of RPS6KB (ribosoma...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Hao, Yan, Shengmin, Khambu, Bilon, Ma, Fengguang, Li, Yong, Chen, Xiaoyun, Martina, Jose. A., Puertollano, Rosa, Li, Yu, Chalasani, Naga, Yin, Xiao-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135624/
https://ncbi.nlm.nih.gov/pubmed/30044707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1490850
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