Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR

The most common mutation in cystic fibrosis patients is a phenylalanine deletion at position 508 (ΔF508) in the CFTR (cystic fibrosis transmembrane conductance regulator) gene. This mutation impairs cell-surface trafficking of CFTR. During cellular stress, core-glycosylated CFTRΔF508 is transported...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Noh, Shin Hye, Gee, Heon Yung, Kim, Yonjung, Piao, He, Kim, Jiyoon, Kang, Chung Min, Lee, Gahyung, Mook-Jung, Inhee, Lee, Yangsin, Cho, Jin Won, Lee, Min Goo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135621/
https://ncbi.nlm.nih.gov/pubmed/29969945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489479
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