Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related Disorders

BACKGRAOUD & AIMS: Aberrant epithelial bicarbonate (HCO(3)(−)) secretion caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with several diseases including cystic fibrosis and pancreatitis. Dynamically regulated ion channel activity and anion...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Kim, Yonjung, Jun, Ikhyun, Shin, Dong Hoon, Yoon, Jihoon G., Piao, He, Jung, Jinsei, Park, Hyun Woo, Cheng, Mary Hongying, Bahar, Ivet, Whitcomb, David C., Lee, Min Goo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889609/
https://ncbi.nlm.nih.gov/pubmed/31561038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.09.003
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