Trypsin Reduces Pancreatic Ductal Bicarbonate Secretion by Inhibiting CFTR Cl(-) channel and Luminal Anion Exchangers

BACKGROUND & AIMS: The effects of trypsin on pancreatic ductal epithelial cells (PDEC) vary among species and depend on localization of proteinase-activated receptor-2 (PAR-2). Bicarbonate secretion is similar in human and guinea pig PDEC; we compared its localization in these cell types and iso...

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Detalhes bibliográficos
Main Authors: Pallagi, Petra, Venglovecz, Viktória, Rakonczay, Zoltán, Borka, Katalin, Korompay, Anna, Ózsvári, Béla, Judák, Linda, Sahin-Tóth, Miklós, Geisz, Andrea, Schnúr, Andrea, Maléth, József, Takács, Tamás, Gray, Mike A., Argent, Barry E., Mayerle, Julia, Lerch, Markus M., Wittmann, Tibor, Hegyi, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273991/
https://ncbi.nlm.nih.gov/pubmed/21893120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.08.039
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