HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy

While the advent of combination antiretroviral therapy (cART) has dramatically increased the life expectancy of HIV-1 infected individuals, paradoxically, however, the prevalence of HIV-1-associated neurocognitive disorders is on the rise. Based on the premise that the cytotoxic HIV-1 protein, trans...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Thangaraj, Annadurai, Periyasamy, Palsamy, Liao, Ke, Bendi, Venkata Sunil, Callen, Shannon, Pendyala, Gurudutt, Buch, Shilpa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper - Basic Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135576/
https://ncbi.nlm.nih.gov/pubmed/29966509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1476810
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