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Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics

Although cocaine exposure has been shown to potentiate neuroinflammation by upregulating glial activation in the brain, the role of mitophagy in this process remains an enigma. In the present study, we sought to examine the role of impaired mitophagy in cocaine-mediated activation of microglia and t...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Thangaraj, Annadurai, Periyasamy, Palsamy, Guo, Ming-Lei, Chivero, Ernest T., Callen, Shannon, Buch, Shilpa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984592/
https://ncbi.nlm.nih.gov/pubmed/30990365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1607686
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