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NLRP3 inflammasome blockade reduces cocaine-induced microglial activation and neuroinflammation

Cocaine use disorder is a major health crisis that is associated with increased oxidative stress and neuroinflammation. While the role of NLRP3 inflammasome in mediating neuroinflammation is well-recognized, whether cocaine induces this response remains unexplored. Based on the premise that cocaine...

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Bibliografische gegevens
Gepubliceerd in:Mol Neurobiol
Hoofdauteurs: Chivero, Ernest T., Thangaraj, Annadurai, Tripathi, Ashutosh, Periyasamy, Palsamy, Guo, Ming-Lei, Buch, Shilpa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026688/
https://ncbi.nlm.nih.gov/pubmed/33417223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02184-x
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