Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Vascular endothelial growth factor receptor-2 (VEGFR2) is a key mediator of angiogenesis and therefore a promising therapeutic target in malignancies including glioblastoma multiforme (GBM). Molecular imaging of VEGFR2 expression may enable patient stratification for antiangiogenic therapy. The goal...

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Detalles Bibliográficos
Publicado en:Theranostics
Autores principales: Mitran, Bogdan, Güler, Rezan, Roche, Francis P., Lindström, Elin, Selvaraju, Ram Kumar, Fleetwood, Filippa, Rinne, Sara S., Claesson-Welsh, Lena, Tolmachev, Vladimir, Ståhl, Stefan, Orlova, Anna, Löfblom, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134937/
https://ncbi.nlm.nih.gov/pubmed/30214632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24395
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