Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Vascular endothelial growth factor receptor-2 (VEGFR2) is a key mediator of angiogenesis and therefore a promising therapeutic target in malignancies including glioblastoma multiforme (GBM). Molecular imaging of VEGFR2 expression may enable patient stratification for antiangiogenic therapy. The goal...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Mitran, Bogdan, Güler, Rezan, Roche, Francis P., Lindström, Elin, Selvaraju, Ram Kumar, Fleetwood, Filippa, Rinne, Sara S., Claesson-Welsh, Lena, Tolmachev, Vladimir, Ståhl, Stefan, Orlova, Anna, Löfblom, John
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134937/
https://ncbi.nlm.nih.gov/pubmed/30214632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24395
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