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Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy

Affibody molecules are engineered scaffold proteins, which demonstrated excellent binding to selected tumor-associated molecular abnormalities in vivo and highly sensitive and specific radionuclide imaging of Her2-expressing tumors in clinics. Recently, we have shown that peptide nucleic acid (PNA)-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Vorobyeva, Anzhelika, Westerlund, Kristina, Mitran, Bogdan, Altai, Mohamed, Rinne, Sara, Sörensen, Jens, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018533/
https://ncbi.nlm.nih.gov/pubmed/29942011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27886-0
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