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Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity

The cannabinoid receptor 1 (CB(1)) is a G protein-coupled receptor (GPCR) that is located primarily in the central nervous system. CB(1) is a therapeutic target which may impact pathways to mediate pain, neurodegenerative disorders, hunger, and drug-seeking behavior. Despite these benefits, developm...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Metab Rev
Prif Awduron: Dopart, Rachel, Lu, Dai, Lichtman, Aron H., Kendall, Debra A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134837/
https://ncbi.nlm.nih.gov/pubmed/29355030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602532.2018.1428342
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