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Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome

Anti-depressant treatment has been found to be associated with the development of Brugada syndrome (BrS) through poorly defined mechanisms. Herein, this study aimed to explore the molecular basis for amitriptyline-induced BrS. The effects of long-term treatments of amitriptyline on Nav1.5 were inves...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteurs: Chen, Xi, Zhu, Chao, Zhou, Hao, Zhang, Yu, Cai, Zhongqi, Wu, Honglin, Ren, Xiaomeng, Gao, Lei, Zhang, Jiancheng, Li, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134322/
https://ncbi.nlm.nih.gov/pubmed/30233406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01230
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