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Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
Brugada syndrome is a life-threatening, inherited arrhythmia disorder associated with autosomal dominant mutations in SCN5A, the gene encoding the human cardiac Na(+ )channel α subunit (Nav1.5). Here, we characterized the biophysical properties of a novel Brugada syndrome-associated Nav1.5 mutation,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749822/ https://ncbi.nlm.nih.gov/pubmed/19706159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-76 |
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