STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells

T-cell acute lymphoblastic leukemia (T-ALL) constitutes an aggressive subset of ALL, the most frequent childhood malignancy. Whereas interleukin-7 (IL-7) is essential for normal T-cell development, it can also accelerate T-ALL development in vivo and leukemia cell survival and proliferation by activ...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Ribeiro, Daniel, Melão, Alice, van Boxtel, Ruben, Santos, Cristina I., Silva, Ana, Silva, Milene C., Cardoso, Bruno A., Coffer, Paul J., Barata, João T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134214/
https://ncbi.nlm.nih.gov/pubmed/30185437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018021063
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