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Characterization of Liver- and Cancer-type-Organic Anion Transporting Polypeptide (OATP) 1B3 Messenger RNA Expression in Normal and Cancerous Human Tissues

BACKGROUND: Membrane transport protein organic anion transporting polypeptide (OATP) 1B3 mediates the cellular uptake of many drugs including anti-cancer drugs (e.g. paclitaxel). In addition to the well-recognized hepatic expression and function of OATP1B3 [herein named liver-type (Lt) OATP1B3], OAT...

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Detalhes bibliográficos
Publicado no:Drug Metab Lett
Main Authors: Alam, Khondoker, Farasyn, Taleah, Ding, Kai, Yue, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133766/
https://ncbi.nlm.nih.gov/pubmed/29577869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312812666180326110146
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