Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic transporters that mediate the uptake of many clinically important drugs, including statins from the blood into the liver. Reduced transport function of OATP1B1 and OATP1B3 can lead to clinically relevant drug-drug i...

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Sparad:
Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Alam, Khondoker, Crowe, Alexandra, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Li, Lang, Yue, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://ncbi.nlm.nih.gov/pubmed/29538325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030855
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