Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic transporters that mediate the uptake of many clinically important drugs, including statins from the blood into the liver. Reduced transport function of OATP1B1 and OATP1B3 can lead to clinically relevant drug-drug i...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Alam, Khondoker, Crowe, Alexandra, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Li, Lang, Yue, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://ncbi.nlm.nih.gov/pubmed/29538325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030855
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