Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic transporters that mediate the uptake of many clinically important drugs, including statins from the blood into the liver. Reduced transport function of OATP1B1 and OATP1B3 can lead to clinically relevant drug-drug i...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Alam, Khondoker, Crowe, Alexandra, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Li, Lang, Yue, Wei
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://ncbi.nlm.nih.gov/pubmed/29538325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030855
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