Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic transporters that mediate the uptake of many clinically important drugs, including statins from the blood into the liver. Reduced transport function of OATP1B1 and OATP1B3 can lead to clinically relevant drug-drug i...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Alam, Khondoker, Crowe, Alexandra, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Li, Lang, Yue, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://ncbi.nlm.nih.gov/pubmed/29538325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030855
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