Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria are important regulators of tumour growth and progression due to their specific role in cancer metabolism and modulation of apoptotic pathways. In this paper we describe that mitochondria-targeted antioxidant SkQ1 designed as a conjugate of decyl-triphenylphosphonium cation (TPP(+)) wit...

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Publicado en:Cell Cycle
Autores principales: Titova, Ekaterina, Shagieva, Galina, Ivanova, Olga, Domnina, Lidiya, Domninskaya, Maria, Strelkova, Olga, Khromova, Natalya, Kopnin, Pavel, Chernyak, Boris, Skulachev, Vladimir, Dugina, Vera
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133338/
https://ncbi.nlm.nih.gov/pubmed/29995559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1496748
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