Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria are important regulators of tumour growth and progression due to their specific role in cancer metabolism and modulation of apoptotic pathways. In this paper we describe that mitochondria-targeted antioxidant SkQ1 designed as a conjugate of decyl-triphenylphosphonium cation (TPP(+)) wit...

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Vydáno v:Cell Cycle
Hlavní autoři: Titova, Ekaterina, Shagieva, Galina, Ivanova, Olga, Domnina, Lidiya, Domninskaya, Maria, Strelkova, Olga, Khromova, Natalya, Kopnin, Pavel, Chernyak, Boris, Skulachev, Vladimir, Dugina, Vera
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133338/
https://ncbi.nlm.nih.gov/pubmed/29995559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1496748
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