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Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria are important regulators of tumour growth and progression due to their specific role in cancer metabolism and modulation of apoptotic pathways. In this paper we describe that mitochondria-targeted antioxidant SkQ1 designed as a conjugate of decyl-triphenylphosphonium cation (TPP(+)) wit...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Titova, Ekaterina, Shagieva, Galina, Ivanova, Olga, Domnina, Lidiya, Domninskaya, Maria, Strelkova, Olga, Khromova, Natalya, Kopnin, Pavel, Chernyak, Boris, Skulachev, Vladimir, Dugina, Vera
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133338/
https://ncbi.nlm.nih.gov/pubmed/29995559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1496748
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