Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria are important regulators of tumour growth and progression due to their specific role in cancer metabolism and modulation of apoptotic pathways. In this paper we describe that mitochondria-targeted antioxidant SkQ1 designed as a conjugate of decyl-triphenylphosphonium cation (TPP(+)) wit...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Titova, Ekaterina, Shagieva, Galina, Ivanova, Olga, Domnina, Lidiya, Domninskaya, Maria, Strelkova, Olga, Khromova, Natalya, Kopnin, Pavel, Chernyak, Boris, Skulachev, Vladimir, Dugina, Vera
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133338/
https://ncbi.nlm.nih.gov/pubmed/29995559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1496748
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