Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria are important regulators of tumour growth and progression due to their specific role in cancer metabolism and modulation of apoptotic pathways. In this paper we describe that mitochondria-targeted antioxidant SkQ1 designed as a conjugate of decyl-triphenylphosphonium cation (TPP(+)) wit...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Titova, Ekaterina, Shagieva, Galina, Ivanova, Olga, Domnina, Lidiya, Domninskaya, Maria, Strelkova, Olga, Khromova, Natalya, Kopnin, Pavel, Chernyak, Boris, Skulachev, Vladimir, Dugina, Vera
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133338/
https://ncbi.nlm.nih.gov/pubmed/29995559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1496748
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