Cellular senescence induces replication stress with almost no affect on DNA replication timing

Organismal aging entails a gradual decline of normal physiological functions and a major contributor to this decline is withdrawal of the cell cycle, known as senescence. Senescence can result from telomere diminution leading to a finite number of population doublings, known as replicative senescenc...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Rivera-Mulia, Juan Carlos, Schwerer, Hélène, Besnard, Emilie, Desprat, Romain, Trevilla-Garcia, Claudia, Sima, Jiao, Bensadoun, Paul, Zouaoui, Anissa, Gilbert, David M., Lemaitre, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133336/
https://ncbi.nlm.nih.gov/pubmed/29963964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1491235
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