DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy

Triple-negative breast cancer (TNBC) is typically aggressive, difficult to treat, and commonly metastasizes to the visceral organs and soft tissues, including the lungs and the brain. Taxanes represent the most effective and widely used therapeutic class in metastatic TNBC but possess limiting adver...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Anticancer Drugs
Main Authors: Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M., Shore, Gordon C., Roulston, Anne
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2018
Teme:
Preclinical Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133219/
https://ncbi.nlm.nih.gov/pubmed/29878901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000653
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