Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models

Systemic chemotherapy using two-drug platinum-based regimens for the treatment of advanced stage non-small cell lung cancer (NSCLC) has largely reached a plateau of effectiveness. Accordingly, efforts to improve survival and quality of life outcomes have more recently focused on the use of molecular...

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Bibliographische Detailangaben
Hauptverfasser: Proia, David A., Sang, Jim, He, Suqin, Smith, Donald L., Sequeira, Manuel, Zhang, Chaohua, Liu, Yuan, Ye, Shuxia, Zhou, Dan, Blackman, Ronald K., Foley, Kevin P., Koya, Keizo, Wada, Yumiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Preclinical Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484281/
https://ncbi.nlm.nih.gov/pubmed/22227828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9790-6
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