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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer

The integration of targeted agents to standard cytotoxic regimens has improved outcomes for patients with colorectal cancer (CRC) over recent years; however this malignancy remains the second leading cause of cancer mortality in industrialized countries. Small molecule inhibitors of heat shock prote...

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Détails bibliographiques
Auteurs principaux: He, Suqin, Smith, Donald L., Sequeira, Manuel, Sang, Jim, Bates, Richard C., Proia, David A.
Format: Artigo
Langue:Inglês
Publié: Springer US 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101249/
https://ncbi.nlm.nih.gov/pubmed/24682747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0095-4
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