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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer

The integration of targeted agents to standard cytotoxic regimens has improved outcomes for patients with colorectal cancer (CRC) over recent years; however this malignancy remains the second leading cause of cancer mortality in industrialized countries. Small molecule inhibitors of heat shock prote...

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Hlavní autoři: He, Suqin, Smith, Donald L., Sequeira, Manuel, Sang, Jim, Bates, Richard C., Proia, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101249/
https://ncbi.nlm.nih.gov/pubmed/24682747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0095-4
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