DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy

Triple-negative breast cancer (TNBC) is typically aggressive, difficult to treat, and commonly metastasizes to the visceral organs and soft tissues, including the lungs and the brain. Taxanes represent the most effective and widely used therapeutic class in metastatic TNBC but possess limiting adver...

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Detalhes bibliográficos
Publicado no:Anticancer Drugs
Main Authors: Bernier, Cynthia, Soliman, Ahmed, Gravel, Michel, Dankner, Matthew, Savage, Paul, Petrecca, Kevin, Park, Morag, Siegel, Peter M., Shore, Gordon C., Roulston, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Preclinical Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133219/
https://ncbi.nlm.nih.gov/pubmed/29878901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000653
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