Inhibition of HIF-1α Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia

Increase of blood brain barrier (BBB) permeability after acute ischemia stroke is a predictor to intracerebral hemorrhage transformation (HT) for tissue plasminogen activator (tPA) thrombolysis and post-endovascular treatment. Previous studies showed that 2-h ischemia induced damage of BBB integrity...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Shen, Yufei, Gu, Jingxia, Liu, Ziyun, Xu, Congying, Qian, Shuxia, Zhang, Xiaoling, Zhou, Beiqun, Guan, Qiaobing, Sun, Yanyun, Wang, Yanping, Jin, Xinchun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132021/
https://ncbi.nlm.nih.gov/pubmed/30233326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00288
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