β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia

Disruption of the blood brain barrier (BBB) within the thrombolytic time window is an antecedent event to intracerebral hemorrhage in ischemic stroke. Our recent studies showed that 2-h cerebral ischemia induced BBB damage in non-infarcted area and secreted matrix metalloproteinase-2 (MMP-2) account...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Sun, Yanyun, Chen, Xi, Zhang, Xinyu, Shen, Xianzhi, Wang, Mengwei, Wang, Xiaona, Liu, Wen-Cao, Liu, Chun-Feng, Liu, Jie, Liu, Wenlan, Jin, Xinchun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558520/
https://ncbi.nlm.nih.gov/pubmed/28855859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00257
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