β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia

Disruption of the blood brain barrier (BBB) within the thrombolytic time window is an antecedent event to intracerebral hemorrhage in ischemic stroke. Our recent studies showed that 2-h cerebral ischemia induced BBB damage in non-infarcted area and secreted matrix metalloproteinase-2 (MMP-2) account...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Sun, Yanyun, Chen, Xi, Zhang, Xinyu, Shen, Xianzhi, Wang, Mengwei, Wang, Xiaona, Liu, Wen-Cao, Liu, Chun-Feng, Liu, Jie, Liu, Wenlan, Jin, Xinchun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558520/
https://ncbi.nlm.nih.gov/pubmed/28855859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00257
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