Inhibition of HIF-1α Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia

Increase of blood brain barrier (BBB) permeability after acute ischemia stroke is a predictor to intracerebral hemorrhage transformation (HT) for tissue plasminogen activator (tPA) thrombolysis and post-endovascular treatment. Previous studies showed that 2-h ischemia induced damage of BBB integrity...

Full description

Saved in:
Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Shen, Yufei, Gu, Jingxia, Liu, Ziyun, Xu, Congying, Qian, Shuxia, Zhang, Xiaoling, Zhou, Beiqun, Guan, Qiaobing, Sun, Yanyun, Wang, Yanping, Jin, Xinchun
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132021/
https://ncbi.nlm.nih.gov/pubmed/30233326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00288
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items