Dl-NBP (Dl-3-N-Butylphthalide) Treatment Promotes Neurological Functional Recovery Accompanied by the Upregulation of White Matter Integrity and HIF-1α/VEGF/Notch/Dll4 Expression

Dl-3-n-butylphthalide (dl-NBP) was approved by the FDA of China for the treatment of acute ischemic stroke. Dl-NBP has been shown to promote neurological functional recovery and enhance white matter integrity using an endothelin-1-induced focal permanent cerebral ischemia model, which could mimic th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Yanping, Shen, Yufei, Liu, Ziyun, Gu, Jingxia, Xu, Congying, Qian, Shuxia, Zhang, Xiaoling, Zhou, Beiqun, Jin, Yuhua, Sun, Yanyun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993069/
https://ncbi.nlm.nih.gov/pubmed/32038259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01595
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