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Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

BACKGROUND: Studies on the relationship between osteoporosis and intervertebral disc degeneration (IVDD) are inconsistent. Therefore, we assessed whether IVDD is affected by vertebral osteoporosis in ovariectomized mice and investigated the underlying pathogenesis of IVDD related to osteoporosis. ME...

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Pubblicato in:Arthritis Res Ther
Autori principali: Xiao, Zhi-feng, He, Jian-bo, Su, Guo-yi, Chen, Mei-hui, Hou, Yu, Chen, Shu-dong, Lin, Ding-kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131954/
https://ncbi.nlm.nih.gov/pubmed/30201052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1701-1
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