Intervertebral Disc Degeneration Is Associated With Aberrant Endplate Remodeling and Reduced Small Molecule Transport

The intervertebral disc is the largest avascular structure in the body, and cells within the disc rely on diffusive transport via vasculature located within the vertebral endplate to receive nutrients, eliminate waste products, and maintain disc health. However, the mechanisms by which small molecul...

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Publicat a:J Bone Miner Res
Autors principals: Ashinsky, Beth G, Bonnevie, Edward D, Mandalapu, Sai A, Pickup, Stephen, Wang, Chao, Han, Lin, Mauck, Robert L, Smith, Harvey E, Gullbrand, Sarah E
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207249/
https://ncbi.nlm.nih.gov/pubmed/32176817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4009
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