Intervertebral Disc Degeneration Is Associated With Aberrant Endplate Remodeling and Reduced Small Molecule Transport

The intervertebral disc is the largest avascular structure in the body, and cells within the disc rely on diffusive transport via vasculature located within the vertebral endplate to receive nutrients, eliminate waste products, and maintain disc health. However, the mechanisms by which small molecul...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Ashinsky, Beth G, Bonnevie, Edward D, Mandalapu, Sai A, Pickup, Stephen, Wang, Chao, Han, Lin, Mauck, Robert L, Smith, Harvey E, Gullbrand, Sarah E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207249/
https://ncbi.nlm.nih.gov/pubmed/32176817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4009
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