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Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice

BACKGROUND: Studies on the relationship between osteoporosis and intervertebral disc degeneration (IVDD) are inconsistent. Therefore, we assessed whether IVDD is affected by vertebral osteoporosis in ovariectomized mice and investigated the underlying pathogenesis of IVDD related to osteoporosis. ME...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Xiao, Zhi-feng, He, Jian-bo, Su, Guo-yi, Chen, Mei-hui, Hou, Yu, Chen, Shu-dong, Lin, Ding-kun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131954/
https://ncbi.nlm.nih.gov/pubmed/30201052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1701-1
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