Ectopic expression of aPKC-mediated phosphorylation in p300 modulates hippocampal neurogenesis, CREB binding and fear memory differently with age

Epigenetic modifications have become an emerging interface that links extrinsic signals to alterations of gene expression that determine cell identity and function. However, direct signaling that regulates epigenetic modifications is unknown. Our previous work demonstrated that phosphorylation of CB...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Syal, Charvi, Seegobin, Matthew, Sarma, Sailendra Nath, Gouveia, Ayden, Hsu, Karolynn, Niibori, Yosuke, He, Ling, Wondisford, Fredric E., Frankland, Paul W., Wang, Jing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131509/
https://ncbi.nlm.nih.gov/pubmed/30201979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31657-2
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