Ectopic expression of aPKC-mediated phosphorylation in p300 modulates hippocampal neurogenesis, CREB binding and fear memory differently with age

Epigenetic modifications have become an emerging interface that links extrinsic signals to alterations of gene expression that determine cell identity and function. However, direct signaling that regulates epigenetic modifications is unknown. Our previous work demonstrated that phosphorylation of CB...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Syal, Charvi, Seegobin, Matthew, Sarma, Sailendra Nath, Gouveia, Ayden, Hsu, Karolynn, Niibori, Yosuke, He, Ling, Wondisford, Fredric E., Frankland, Paul W., Wang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131509/
https://ncbi.nlm.nih.gov/pubmed/30201979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31657-2
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