טוען...
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer
The degree of intrinsic and interpatient phenotypic heterogeneity and its role in tumour evolution is poorly understood. Phenotypic drifts can be transmitted via inheritable transcriptional programs. Cell-type specific transcription is maintained through the activation of epigenetically-defined regu...
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| הוצא לאור ב: | Nat Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130800/ https://ncbi.nlm.nih.gov/pubmed/30038216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0091-x |
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